Ifitm1^{Gt(OST471536)Lex}
Gene trapped Allele Detail

Summary

• Symbol: Ifitm1^{Gt(OST471536)Lex}
• Name: interferon induced transmembrane protein 1; gene trap OST471536, Lexicon Genetics
• MGI ID: MGI:4328297
• Synonyms: LEXKO-1373
• Gene: Ifitm1 Location: Chr7:140547342-140549740 bp, + strand Genetic Position: Chr7, 86.2 cM, cytoband F5
• Alliance: Ifitm1^{Gt(OST471536)Lex} page

Mutation origin

• Mutant Cell Line: OST471536
• Germline Transmission: Earliest citation of germline transmission: J:82809
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• Mutation details: Retroviral insertion disrupted the gene upstream of the first coding exon (NM_026820.2). RT-PCR analysis revealed that the transcript was absent in the homozygous mutant mice. (J:82809)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  OST471536	CG670795 ; (MGI Seq Detail)	3' RACE	Chr7:140548150-140549691 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  52 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ifitm1 Mutation: 42 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)