Rfx1^{Gt(RRO347)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Rfx1^{Gt(RRO347)Byg}
• Name: regulatory factor X, 1 (influences HLA class II expression); gene trap RRO347, BayGenomics
• MGI ID: MGI:4329124
• Gene: Rfx1 Location: Chr8:84793463-84823621 bp, + strand Genetic Position: Chr8, 40.28 cM
• Alliance: Rfx1^{Gt(RRO347)Byg} page

Mutation origin

• Mutant Cell Line: RRO347
• Germline Transmission: Earliest citation of germline transmission: J:151670
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT2Lxf Vector Type: gene trap
• The gene trap vector inserted into intron 2. (J:151670)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRO347	CG671685 ; (MGI Seq Detail)	5' RACE	Chr8:84800542-84800696 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  17 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Rfx1 Mutation: 46 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)