M1ap^{Gt(RRO290)Byg}
Gene trapped Allele Detail

Summary

• Symbol: M1ap^{Gt(RRO290)Byg}
• Name: meiosis 1 associated protein; gene trap RRO290, BayGenomics
• MGI ID: MGI:4329148
• Synonyms: M1ap^{Gt(RR0290)Byg}, M1ap^lz, RR0290
• Gene: M1ap Location: Chr6:82923889-83007290 bp, + strand Genetic Position: Chr6, 35.94 cM
• Alliance: M1ap^{Gt(RRO290)Byg} page

Mutation origin

• Mutant Cell Line: RRO290
• Germline Transmission: Earliest citation of germline transmission: J:194507
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT2Lxf Vector Type: gene trap
• Mutation details: The gene trap vector inserted into intron 6. Western blot anlaysis confirms the absence of protein expression in the testes in some mice and reduced expression in others. This allele is hypomorphic. (J:194507)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRO290	CG671710 ; (MGI Seq Detail)	5' RACE	Chr6:82982486-82983432 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	34 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any M1ap Mutation: 25 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)