Lrsam1^{Gt(RRK461)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Lrsam1^{Gt(RRK461)Byg}
• Name: leucine rich repeat and sterile alpha motif containing 1; gene trap RRK461, BayGenomics
• MGI ID: MGI:4329496
• Gene: Lrsam1 Location: Chr2:32815228-32851626 bp, - strand Genetic Position: Chr2, 22.09 cM
• Alliance: Lrsam1^{Gt(RRK461)Byg} page

Mutation origin

• Mutant Cell Line: RRK461
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT2Lxf Vector Type: gene trap
• Mutation details: The gene trap vector, RRK461, inserted at position 1149 of intron 22. Western blot analysis confirms the absence of protein expression. (J:196447)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRK461	CG672080 ; (MGI Seq Detail)	5' RACE	Chr2:32822105-32830291 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  18 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Lrsam1 Mutation: 32 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)