Arhgap17^{Gt(RRN062)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Arhgap17^{Gt(RRN062)Byg}
• Name: Rho GTPase activating protein 17; gene trap RRN062, BayGenomics
• MGI ID: MGI:4329627
• Synonyms: Arhgap17^m
• Gene: Arhgap17 Location: Chr7:122878441-122969138 bp, - strand Genetic Position: Chr7, 67.42 cM, cytoband F3
• Alliance: Arhgap17^{Gt(RRN062)Byg} page

Mutation origin

• Mutant Cell Line: RRN062
• Germline Transmission: Earliest citation of germline transmission: J:277297
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: A gene trap vector (pGT0lxf) consisting of an En2 splicing acceptor sequence (SA), beta-geo (lacZ fused with neomycin transphosphorylase fusion gene) and SV40 poly(A) site (pA), was inserted into intron 2. Western blot analysis confirmed the absence of protein expression in the small intestine of homozygous mutant mice, suggesting that this likely a null allele. (J:277297)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRN062	CG672218 ; (MGI Seq Detail)	5' RACE	Chr7:122930451-122969128 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  51 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arhgap17 Mutation: 90 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)