Cttn^{Gt(RRS284)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Cttn^{Gt(RRS284)Byg}
• Name: cortactin; gene trap RRS284, BayGenomics
• MGI ID: MGI:4330257
• Gene: Cttn Location: Chr7:143989468-144024743 bp, - strand Genetic Position: Chr7, 88.84 cM
• Alliance: Cttn^{Gt(RRS284)Byg} page

Mutation origin

• Mutant Cell Line: RRS284
• Germline Transmission: Earliest citation of germline transmission: J:158029
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: The gene trap vector inserted between exon 7 and 8. Reduced protein expression was confirmed by western blot analysis on heterozygous mouse embryonic fibroblasts. In situ hybridization confirmed ubiquitous expression of the lacZ fusion transcript.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRS284	CG784419 ; (MGI Seq Detail)	5' RACE	Chr7:144010179-144014949 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  6 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:

1 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cttn Mutation: 28 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)