Ppp2r5c^{Gt(XP0444)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Ppp2r5c^{Gt(XP0444)Wtsi}
• Name: protein phosphatase 2, regulatory subunit B', gamma; gene trap XP0444, Wellcome Trust Sanger Institute
• MGI ID: MGI:4331551
• Synonyms: B56gamma^-, B56gamma^XP0444
• Gene: Ppp2r5c Location: Chr12:110413554-110549496 bp, + strand Genetic Position: Chr12, 60.56 cM, cytoband F2
• Alliance: Ppp2r5c^{Gt(XP0444)Wtsi} page

Mutation origin

• Mutant Cell Line: XP0444
• Germline Transmission: Earliest citation of germline transmission: J:210365
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: pGT0lxf
• Mutation details: The gene trap vector inserted in the second intron of the gene. Semi-quantitative RT-PCR and western blot analyses confirmed the absence of wild-type transcript and protein in tissues from homozygous mice. (J:210365)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XP0444	CG869555 ; (MGI Seq Detail)	5' RACE	Chr12:110452216-110489123 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  402 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	16 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp2r5c Mutation: 47 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)