Llgl2^{Gt(XS0846)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Llgl2^{Gt(XS0846)Wtsi}
• Name: LLGL2 scribble cell polarity complex component; gene trap XS0846, Wellcome Trust Sanger Institute
• MGI ID: MGI:4331862
• Synonyms: Lgl2^tm2Vv
• Gene: Llgl2 Location: Chr11:115714875-115746606 bp, + strand Genetic Position: Chr11, 80.91 cM
• Alliance: Llgl2^{Gt(XS0846)Wtsi} page

Mutation origin

• Mutant Cell Line: XS0846
• Germline Transmission: Earliest citation of germline transmission: J:174237
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxf
• Mutation details: The gene trap vector was inserted into intron 2. Western blot analysis confirmed the absence of protein expression in homozygous mice. (J:174237)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XS0846	CG869925 ; (MGI Seq Detail)	5' RACE	Chr11:115714898-115725727 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  449 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Llgl2 Mutation: 295 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)