Nipbl^{Gt(RRS564)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Nipbl^{Gt(RRS564)Byg}
• Name: NIPBL cohesin loading factor; gene trap RRS564, BayGenomics
• MGI ID: MGI:4332250
• Gene: Nipbl Location: Chr15:8320101-8473947 bp, - strand Genetic Position: Chr15, 3.82 cM, cytoband A2
• Alliance: Nipbl^{Gt(RRS564)Byg} page

Bone and heart development abnormalities in Nipbl^{Gt(RRS564)Byg}/Nipbl⁺ mice

Show the 3 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: RRS564
• Germline Transmission: Earliest citation of germline transmission: J:154117
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• The gene trap vector inserted into exon 1. (J:154117)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRS564	CG887217 ; (MGI Seq Detail)	5' RACE	Chr15:8473612-8473817 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  56 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Mice Carrying this Mutation:	12 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	23 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nipbl Mutation: 124 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 10 reference(s)