Zdhhc13^{Gt(AC0492)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Zdhhc13^{Gt(AC0492)Wtsi}
• Name: zinc finger, DHHC domain containing 13; gene trap AC0492, Wellcome Trust Sanger Institute
• MGI ID: MGI:4338023
• Gene: Zdhhc13 Location: Chr7:48438751-48477188 bp, + strand Genetic Position: Chr7, 31.11 cM, cytoband B3
• Alliance: Zdhhc13^{Gt(AC0492)Wtsi} page

Abnormal follicles, lack of hair and thickened epidermis in Zdhhc13^{Gt(AC0492)Wtsi}/Zdhhc13^{Gt(AC0492)Wtsi} mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: AC0492
• Germline Transmission: Earliest citation of germline transmission: J:161519
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: A LacZ gene was inserted within intron 1 as part of a gene trap. RT-PCR confirmed the absence of transcript expression in the brain, liver and kidney. (J:161519, J:191129)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AC0492	CL256372 ; (MGI Seq Detail)	5' RACE	Chr7:48438823-48438884 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

12 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zdhhc13 Mutation: 30 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)