Dyrk1a^{Gt(XQ0369)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Dyrk1a^{Gt(XQ0369)Wtsi}
• Name: dual-specificity tyrosine phosphorylation regulated kinase 1a; gene trap XQ0369, Wellcome Trust Sanger Institute
• MGI ID: MGI:4338238
• Synonyms: Dyrk1a^m1
• Gene: Dyrk1a Location: Chr16:94370869-94496376 bp, + strand Genetic Position: Chr16, 55.3 cM
• Alliance: Dyrk1a^{Gt(XQ0369)Wtsi} page

Mutation origin

• Mutant Cell Line: XQ0369
• Germline Transmission: Earliest citation of germline transmission: J:224899
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxf
• Mutation details: The beta-geo containing gene trap vector inserted in intron 4 resulting in disruption of the 321 amino acid kinase domain. (J:224899)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  XQ0369	CL256654 ; (MGI Seq Detail)	5' RACE	Chr16:94466858-94466962 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  105 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dyrk1a Mutation: 115 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)