Aspm^{Gt(AA0137)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Aspm^{Gt(AA0137)Wtsi}
• Name: abnormal spindle microtubule assembly; gene trap AA0137, Wellcome Trust Sanger Institute
• MGI ID: MGI:4345319
• Synonyms: Aspm^1-7
• Gene: Aspm Location: Chr1:139382510-139421829 bp, + strand Genetic Position: Chr1, 61.45 cM, cytoband F
• Alliance: Aspm^{Gt(AA0137)Wtsi} page

Mutation origin

• Mutant Cell Line: AA0137
• Germline Transmission: Earliest citation of germline transmission: J:164424
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: The gene trap vector was determined to have integrated between exons 7 and 8 such that the protein product contains only the microtubule binding domain. (J:164424)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AA0137	CL524973 ; (MGI Seq Detail)	5' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Disease models

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Aspm Mutation: 138 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)