Asf1a^{Gt(AL0673)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Asf1a^{Gt(AL0673)Wtsi}
• Name: anti-silencing function 1A histone chaperone; gene trap AL0673, Wellcome Trust Sanger Institute
• MGI ID: MGI:4345510
• Synonyms: AL, Asf1a^ALO673
• Gene: Asf1a Location: Chr10:53473057-53485321 bp, + strand Genetic Position: Chr10, 27.24 cM, cytoband B3
• Alliance: Asf1a^{Gt(AL0673)Wtsi} page

Asf1a^{Gt(AL0673)Wtsi}/Asf1a^{Gt(AL0673)Wtsi} embryos are developmentally arrested at E8.5

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: AL0673
• Germline Transmission: Earliest citation of germline transmission: J:177420
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: The gene trap vector inserted 640 bp downstream of exon 2. Expression of Mcm9 transcripts are normal in homozygous mice. (J:177420)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AL0673	CL525193 ; (MGI Seq Detail)	5' RACE	Chr10:53473272-53478558 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  60 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Schematic of the insertion sites of the Asf1a^{Gt(AL0673)Wtsi}, Del(10Mcm9-Asf1a)1Byg, Mcm9^{Gt(AW0655)Wtsi}, and Mcm9^Gt(XG743)Byg gene traps

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Asf1a Mutation: 35 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)