Prkab2^{Gt(AL0483)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Prkab2^{Gt(AL0483)Wtsi}
• Name: protein kinase, AMP-activated, beta 2 non-catalytic subunit; gene trap AL0483, Wellcome Trust Sanger Institute
• MGI ID: MGI:4345788
• Synonyms: beta2mut
• Gene: Prkab2 Location: Chr3:97565527-97581128 bp, + strand Genetic Position: Chr3, 42.25 cM
• Alliance: Prkab2^{Gt(AL0483)Wtsi} page

Mutation origin

• Mutant Cell Line: AL0483
• Germline Transmission: Earliest citation of germline transmission: J:186658
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: The gene trap vector inserted into intron 2. Western blot analysis confirmed the absence of protein expression in the brain, heart, liver, pancreas, kidney, gastrocnemius and brown fat. (J:186658)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AL0483	CL525556 ; (MGI Seq Detail)	5' RACE	Chr3:97565859-97566081 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prkab2 Mutation: 29 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)