Atrx^{Gt(P034D09)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Atrx^{Gt(P034D09)Wrst}
• Name: ATRX, chromatin remodeler; gene trap P034D09, German Gene Trap Consortium
• MGI ID: MGI:4351061
• Gene: Atrx Location: ChrX:104841221-104972978 bp, - strand Genetic Position: ChrX, 47.26 cM
• Alliance: Atrx^{Gt(P034D09)Wrst} page

Posterior patterning and heart defects in Atrx^{Gt(P034C09)Wrst}/Y chimera at E9

Show the 7 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: P034D09
• Germline Transmission: Earliest citation of germline transmission: J:160967
• Parent Cell Line: IDG3.2 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S6/SvEvTac)F1

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: eFlpROSAbetageo
• Mutation details: The sequence does show overlap with the Atrx gene. There are a lot of mismatches in the alignment (only 94% identity).
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  P034D09	FI850457 ; (MGI Seq Detail)	5' RACE	unknown
  * GRCm39; (strand of gene trap mutagenesis)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atrx Mutation: 78 strains or lines available

Notes

Additional information on the construction of chimeric mice reported in J:160967 can be found at this link

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)