Nqo1^tm1Msho
Targeted Allele Detail

Summary

• Symbol: Nqo1^tm1Msho
• Name: NAD(P)H dehydrogenase, quinone 1; targeted mutation 1, Minho Shong
• MGI ID: MGI:4353051
• Gene: Nqo1 Location: Chr8:108114857-108129838 bp, - strand Genetic Position: Chr8, 54.08 cM
• Alliance: Nqo1^tm1Msho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151045
• Parent Cell Line: J1 (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A 3425 bp fragment including exons 5 and 6 was replaced with a pgk-neo cassette via homologous recombination. (J:151045)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nqo1 Mutation: 26 strains or lines available

References

• Original: J:151045 Hwang JH, et al., Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice. Diabetes. 2009 Apr;58(4):965-74
• All: 5 reference(s)