Nrep^tm1Wcw
Targeted Allele Detail

Summary

• Symbol: Nrep^tm1Wcw
• Name: neuronal regeneration related protein; targeted mutation 1, William C Wetsel
• MGI ID: MGI:4353245
• Synonyms: P311^-
• Gene: Nrep Location: Chr18:33570072-33597082 bp, - strand Genetic Position: Chr18, 18.18 cM
• Alliance: Nrep^tm1Wcw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151154
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The third and part of the fourth exon were replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on skeletal muscle extracts and by RT-PCR analysis on hippocampus and cerebellum extracts. (J:151154)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrep Mutation: 14 strains or lines available

References

• Original: J:151154 Taylor GA, et al., Behavioral characterization of P311 knockout mice. Genes Brain Behav. 2008 Oct;7(7):786-95
• All: 8 reference(s)