Antxr1^tm1.2Bstc
Targeted Allele Detail

Summary

• Symbol: Antxr1^tm1.2Bstc
• Name: anthrax toxin receptor 1; targeted mutation 1.2, Brad St Croix
• MGI ID: MGI:4353383
• Synonyms: TEM8^-
• Gene: Antxr1 Location: Chr6:87110835-87312757 bp, - strand Genetic Position: Chr6, 37.94 cM
• Alliance: Antxr1^tm1.2Bstc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150947
• Parent Cell Line: v6.4 (ES Cell)
• Strain of Origin: (C57BL/6J x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination removed exon 1. The absence of protein expression was confirmed by westrn blot analysis on tumor-derived endothelial cells. (J:150947)

Expression

In Mice Carrying this Mutation:	11 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Antxr1 Mutation: 30 strains or lines available

References

• Original: J:150947 Cullen M, et al., Host-derived tumor endothelial marker 8 promotes the growth of melanoma. Cancer Res. 2009 Aug 1;69(15):6021-6
• All: 6 reference(s)