Szt2^m1Frk
Chemically induced Allele Detail

Summary

• Symbol: Szt2^m1Frk
• Name: SZT2 subunit of KICSTOR complex; mutation 1, Wayne N Frankel
• MGI ID: MGI:4353995
• Gene: Szt2 Location: Chr4:118219940-118266470 bp, - strand Genetic Position: Chr4, 54.61 cM
• Alliance: Szt2^m1Frk page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: A T to A mutation was induced by ENU in the exon 32 splice site donor resulting in inclusion of intron 32 in the mutant transcript. Northern blot analysis indicates about a 4 fold increase in mRNA expression in whole brains from homozygous mice. (J:150942)

Expression

In Mice Carrying this Mutation:

19 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Szt2 Mutation: 94 strains or lines available

References

• Original: J:150942 Frankel WN, et al., Szt2, a novel gene for seizure threshold in mice. Genes Brain Behav. 2009 Jul;8(5):568-76
• All: 1 reference(s)