Ip6k2^tm1Dlin
Targeted Allele Detail

Summary

• Symbol: Ip6k2^tm1Dlin
• Name: inositol hexaphosphate kinase 2; targeted mutation 1, D J Lindner
• MGI ID: MGI:4354090
• Synonyms: IHPK2^-
• Gene: Ip6k2 Location: Chr9:108660995-108683536 bp, + strand Genetic Position: Chr9, 59.63 cM, cytoband F2
• Alliance: Ip6k2^tm1Dlin page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151345
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The first 202 bp of exon 2 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on tail snip extracts. (J:151345)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ip6k2 Mutation: 26 strains or lines available

References

• Original: J:151345 Morrison BH, et al., Gene deletion of inositol hexakisphosphate kinase 2 predisposes to aerodigestive tract carcinoma. Oncogene. 2009 Jun 25;28(25):2383-92
• All: 2 reference(s)