Tg(APOE-GHRL)1Jagu
Transgene Detail

Summary

• Symbol: Tg(APOE-GHRL)1Jagu
• Name: transgene insertion 1, Jesus A Gutierrez
• MGI ID: MGI:4354174
• Transgene: Tg(APOE-GHRL)1Jagu Location: unknown
• Alliance: Tg(APOE-GHRL)1Jagu page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(APOE-GHRL)1Jagu expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  GHRL (51738)

  Ghrl	(MGI:1930008)

• Mutation details: The open reading frame for the human pre-pro-ghrelin was cloned with the addition of a 5' Kozak sequence into a transgene vector driven by the human apoE gene promoter and its hepatic control region for specific liver tissue expression. Functional expression of the transgene was determined by immunoprecipitation of human ghrelin from the blood. (J:151420)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:151420 Kirchner H, et al., GOAT links dietary lipids with the endocrine control of energy balance. Nat Med. 2009 Jul;15(7):741-5
• All: 1 reference(s)