Afdn^tm2Ytk
Targeted Allele Detail

Summary

• Symbol: Afdn^tm2Ytk
• Name: afadin, adherens junction formation factor; targeted mutation 2, Yoshimi Takai
• MGI ID: MGI:4354298
• Synonyms: afadin^flox
• Gene: Afdn Location: Chr17:13980735-14126059 bp, + strand Genetic Position: Chr17, 8.95 cM, cytoband A2
• Alliance: Afdn^tm2Ytk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151436
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and a floxed neo cassette was inserted downstream of exon 2. (J:151436)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Afdn Mutation: 84 strains or lines available

References

• Original: J:151436 Majima T, et al., Involvement of afadin in the formation and remodeling of synapses in the hippocampus. Biochem Biophys Res Commun. 2009 Aug 7;385(4):539-44
• All: 15 reference(s)