Tg(Dbh-icre)1Gsc
Transgene Detail

Summary

• Symbol: Tg(Dbh-icre)1Gsc
• Name: transgene insertion 1, Gunther Schutz
• MGI ID: MGI:4355551
• Synonyms: DBHCre, DBHiCre
• Transgene: Tg(Dbh-icre)1Gsc Location: unknown
• Alliance: Tg(Dbh-icre)1Gsc page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Dbh-icre)1Gsc expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Dbh

• Mutation details: Using ET recombination, the coding sequence of iCre, followed by the bovine growth hormone polyadenylation signal, was introduced in-frame with the ATG of the Dbh gene in a PAC. The 150 kb transgenic construct was injected into he male pronuclei of fertilized C57BL/6 oocytes. (J:128636)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dbh (species not specified) Summary of all recombinase alleles driven by Dbh. Comparative matrix view of recombinase activities

Disease models

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:128636 Stanke M, et al., Target-dependent specification of the neurotransmitter phenotype: cholinergic differentiation of sympathetic neurons is mediated in vivo by gp 130 signaling. Development. 2006 Jan;133(1):141-50
• All: 50 reference(s)