Fancm^tm1.1Htr
Targeted Allele Detail

Summary

• Symbol: Fancm^tm1.1Htr
• Name: Fanconi anemia, complementation group M; targeted mutation 1.1, Hein Te Riele
• MGI ID: MGI:4355560
• Synonyms: Fancm^delta2
• Gene: Fancm Location: Chr12:65122377-65178832 bp, + strand Genetic Position: Chr12, 27.21 cM
• Alliance: Fancm^tm1.1Htr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151714
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination removed exon 2 and the neo cassette. The absence of protein expression was confirmed by western blot analysis on mouse embryonic fibroblast extracts. (J:151714)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fancm Mutation: 120 strains or lines available

References

• Original: J:151714 Bakker ST, et al., Fancm-deficient mice reveal unique features of Fanconi anemia complementation group M. Hum Mol Genet. 2009 Sep 15;18(18):3484-95
• All: 1 reference(s)