Gper1^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gper1^tm1Dgen
• Name: G protein-coupled estrogen receptor 1; targeted mutation 1, Deltagen
• MGI ID: MGI:4355679
• Synonyms: Gpr30-lacZ
• Gene: Gper1 Location: Chr5:139408906-139413555 bp, + strand Genetic Position: Chr5, 78.58 cM, cytoband G1
• Alliance: Gper1^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:151816
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: 349 bp of the open reading frame in exon 3 were replaced with an IRES, lacZ, and neo cassette. The predicted protein lacks the first two transmembrane domain and the first intra- and extracellular loop. (J:151816)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gper1 Mutation: 30 strains or lines available

References

• Original: J:151816 Isensee J, et al., Expression pattern of G protein-coupled receptor 30 in LacZ reporter mice. Endocrinology. 2009 Apr;150(4):1722-30
• All: 3 reference(s)