Tg(Ppp1r1b-cre)1Meeh
Transgene Detail

Summary

• Symbol: Tg(Ppp1r1b-cre)1Meeh
• Name: transgene insertion 1, Michelle E Ehrlich
• MGI ID: MGI:4356000
• Synonyms: A11K20IRESCre, D32-Cre, D9-Cre, DARPP-32Cre
• Transgene: Tg(Ppp1r1b-cre)1Meeh Location: unknown
• Alliance: Tg(Ppp1r1b-cre)1Meeh page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Ppp1r1b-cre)1Meeh expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Ppp1r1b

• Mutation details: An IRES-cre fragment with a nuclear localization signal sequence (nls) and an SV40 polyA sequence was inserted into a plasmid containing genomic fragments of Ppp1rb1 from 3 clones. The transgenic construct was injected into fertilized C57BL/6 oocytes. Two potential founders were obtained but only one founder was successfully bred to generate the line. Insertion of a single copy of the transgene was verified by Southern blot. (J:127863)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ppp1r1b (species not specified) Summary of all recombinase alleles driven by Ppp1r1b. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:127863 Bogush AI, et al., DARPP-32 genomic fragments drive Cre expression in postnatal striatum. Genesis. 2005 May;42(1):37-46
• All: 11 reference(s)