Ghsr^tm1Mws
Targeted Allele Detail

Summary

• Symbol: Ghsr^tm1Mws
• Name: growth hormone secretagogue receptor; targeted mutation 1, Mark W Sleeman
• MGI ID: MGI:4356103
• Synonyms: ghrelin receptor knockout
• Gene: Ghsr Location: Chr3:27425500-27432159 bp, + strand Genetic Position: Chr3, 10.86 cM
• Alliance: Ghsr^tm1Mws page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152003
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exon 1 of the locus was precisely deleted and replaced with an in-frame lacZ reporter gene and a floxed neomycin-selectable marker. (J:152003)

Generation of the Ghsr^tm1Mws allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ghsr Mutation: 27 strains or lines available

References

• Original: J:152003 LeSauter J, et al., Stomach ghrelin-secreting cells as food-entrainable circadian clocks. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13582-7
• All: 2 reference(s)