Ipw^tm1Jbro
Targeted Allele Detail

Summary

• Symbol: Ipw^tm1Jbro
• Name: imprinted gene in the Prader-Willi syndrome region; targeted mutation 1, Jurgen Brosius
• MGI ID: MGI:4356427
• Gene: Ipw Location: Chr7:59268906-59328626 bp, - strand Genetic Position: Chr7, 34.0 cM

Mutation origin

• Germline Transmission: Unknown
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Not Specified)
• Mutation: Insertion
• Mutation details: A cassette containing a puromycin resistance gene, a loxP site, and the 3' half of the HPRT mini-gene, was inserted 3' of Ipw. (J:152022)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ipw Mutation: 0 strains or lines available

Notes

Cre mediated recombination of this allele in combination with Snord116^tm1Jbro yields Del(7Ipw-Snord116)1Jbro.

References

• Original: J:152022 Skryabin BV, et al., Deletion of the MBII-85 snoRNA gene cluster in mice results in postnatal growth retardation. PLoS Genet. 2007 Dec 28;3(12):e235
• All: 1 reference(s)