Bicc1^tm1Bdc
Targeted Allele Detail

Summary

• Symbol: Bicc1^tm1Bdc
• Name: BicC family RNA binding protein 1; targeted mutation 1, Daniel B Constam
• MGI ID: MGI:4356450
• Gene: Bicc1 Location: Chr10:70758662-70995530 bp, - strand Genetic Position: Chr10, 36.75 cM
• Alliance: Bicc1^tm1Bdc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152173
• Parent Cell Line: GS1 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: Exons 5 through 11 were replaced with a neo cassette. This deletion splices exon 4 to exon 12 out of frame giving rise to a premature stop codon. (J:152173)

Expression

In Mice Carrying this Mutation:	38 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bicc1 Mutation: 65 strains or lines available

References

• Original: J:152173 Maisonneuve C, et al., Bicaudal C, a novel regulator of Dvl signaling abutting RNA-processing bodies, controls cilia orientation and leftward flow. Development. 2009 Sep;136(17):3019-30
• All: 4 reference(s)