Rbm15^tm1Swm
Targeted Allele Detail

Summary

• Symbol: Rbm15^tm1Swm
• Name: RNA binding motif protein 15; targeted mutation 1, Stephan W Morris
• MGI ID: MGI:4357897
• Synonyms: Rbm15^flox
• Gene: Rbm15 Location: Chr3:107232737-107240989 bp, - strand Genetic Position: Chr3, 46.83 cM
• Alliance: Rbm15^tm1Swm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152262
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 1. (J:152262)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbm15 Mutation: 30 strains or lines available

References

• Original: J:152262 Niu C, et al., c-Myc is a target of RNA-binding motif protein 15 in the regulation of adult hematopoietic stem cell and megakaryocyte development. Blood. 2009 Sep 3;114(10):2087-96
• All: 1 reference(s)