Kif7^tm1.2Hui
Targeted Allele Detail

Summary

• Symbol: Kif7^tm1.2Hui
• Name: kinesin family member 7; targeted mutation 1.2, Chi-chung Hui
• MGI ID: MGI:4357956
• Synonyms: Kif7^-, Kif7^del
• Gene: Kif7 Location: Chr7:79347846-79365468 bp, - strand Genetic Position: Chr7, 45.09 cM, cytoband D2
• Alliance: Kif7^tm1.2Hui page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152259
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination was used to remove exons 2 through 4. The absence of protein expression was confirmed by western blot analysis on E10.5 embryo extracts. (J:152259)

Expression

In Mice Carrying this Mutation:	19 assay results
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif7 Mutation: 40 strains or lines available

References

• Original: J:152259 Cheung HO, et al., The kinesin protein Kif7 is a critical regulator of Gli transcription factors in mammalian hedgehog signaling. Sci Signal. 2009;2(76):ra29
• All: 10 reference(s)