Bcl11atm1Pwt
Targeted Allele Detail
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Symbol: |
Bcl11atm1Pwt |
Name: |
BCL11 transcription factor A; targeted mutation 1, Philip W Tucker |
MGI ID: |
MGI:4358087 |
Synonyms: |
Bcl11afl |
Gene: |
Bcl11a Location: Chr11:24028056-24124123 bp, + strand Genetic Position: Chr11, 14.41 cM
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Alliance: |
Bcl11atm1Pwt page
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Germline Transmission: |
Earliest citation of germline transmission:
J:151995
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: An Frt-flanked neo cassette and lox-P flanked exon 1 were inserted upstream of exon 2. Flp mediated recombination removed the neo-cassette. Cre-mediated recombination will remove exon 1, along with 1.5kb of its upstream sequence containing an ultraconserved noncoding region.
(J:151995, J:207383)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Bcl11a Mutation: |
44 strains or lines available
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Original: |
J:151995 Sankaran VG, et al., Developmental and species-divergent globin switching are driven by BCL11A. Nature. 2009 Aug 27;460(7259):1093-7 |
All: |
8 reference(s) |
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