Stk4^tm1.1Wtao
Targeted Allele Detail

Summary

• Symbol: Stk4^tm1.1Wtao
• Name: serine/threonine kinase 4; targeted mutation 1.1, Wufan Tao
• MGI ID: MGI:4358199
• Synonyms: Mst1^fl
• Gene: Stk4 Location: Chr2:163916033-163997444 bp, + strand Genetic Position: Chr2, 84.6 cM, cytoband H3
• Alliance: Stk4^tm1.1Wtao page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152323
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt flanked neo cassette with a 3' loxP site was inserted upstream of exon 4 and an additional loxP site was inserted downstream of exon 4. The neo cassette was removed by germ line, flp mediated recombination leaving exon 4 floxed. (J:152323)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk4 Mutation: 74 strains or lines available

References

• Original: J:152323 Dong Y, et al., A cell-intrinsic role for Mst1 in regulating thymocyte egress. J Immunol. 2009 Sep 15;183(6):3865-72
• All: 7 reference(s)