Nmur2^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Nmur2^tm1Dgen
• Name: neuromedin U receptor 2; targeted mutation 1, Deltagen
• MGI ID: MGI:4358245
• Gene: Nmur2 Location: Chr11:55915816-55931813 bp, - strand Genetic Position: Chr11, 33.39 cM
• Alliance: Nmur2^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152371
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• The sequence coding for amino acids 72-125 was replaced with a lacZ gene and a neo cassette. (J:152371)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nmur2 Mutation: 28 strains or lines available

References

• Original: J:152371 Peier A, et al., The antiobesity effects of centrally administered neuromedin U and neuromedin S are mediated predominantly by the neuromedin U receptor 2 (NMUR2). Endocrinology. 2009 Jul;150(7):3101-9
• All: 2 reference(s)