Tg(Pbsn-Hpn,-GFP)DVv
Transgene Detail

Summary

• Symbol: Tg(Pbsn-Hpn,-GFP)DVv
• Name: transgene insertion D, Valeri Vasioukhin
• MGI ID: MGI:4358581
• Synonyms: PB-hepsin Line D, Tg(Pbsn-Hpn,-hrGFP)DVv
• Transgene: Tg(Pbsn-Hpn,-GFP)DVv Location: unknown
• Alliance: Tg(Pbsn-Hpn,-GFP)DVv page

Transgene origin

• Strain of Origin: C57BL/6 x CBA

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Pbsn-Hpn,-GFP)DVv expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Hpn (MGI:1196620)

• Mutation details: A transgenic construct containing a modified rat probasin (Pbsn) promoter, beta globin intron, mouse hepsin (Hpn) full length cDNA , and an IRES-humanized Renilla (hr) GFP cassette was injected into C57BL/6 x CBA fertilized embryos. Founder line D was subsequently established. (J:92562)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Pbsn-Hpn,-GFP)DVv

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:92562 Klezovitch O, et al., Hepsin promotes prostate cancer progression and metastasis. Cancer Cell. 2004 Aug;6(2):185-95
• All: 1 reference(s)