App^tm1.2Zhe
Targeted Allele Detail

Summary

• Symbol: App^tm1.2Zhe
• Name: amyloid beta precursor protein; targeted mutation 1.2, Hui Zheng
• MGI ID: MGI:4359012
• Synonyms: App^deltaE3
• Gene: App Location: Chr16:84751236-84972187 bp, - strand Genetic Position: Chr16, 46.92 cM, cytoband C3-qter
• Alliance: App^tm1.2Zhe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152457
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Germ line, cre mediated recombination removed exon 3 and the neo cassette. (J:152457)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any App Mutation: 103 strains or lines available

References

• Original: J:152457 Wang Z, et al., Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. J Neurosci. 2009 Sep 2;29(35):10788-801
• All: 3 reference(s)