Stard13^tm1Ioln
Targeted Allele Detail

Summary

• Symbol: Stard13^tm1Ioln
• Name: StAR related lipid transfer domain containing 13; targeted mutation 1, Irene Oi Lin Ng
• MGI ID: MGI:4359214
• Synonyms: DLC2^-
• Gene: Stard13 Location: Chr5:150960975-151157301 bp, - strand Genetic Position: Chr5, 89.82 cM
• Alliance: Stard13^tm1Ioln page

Decrease in adipose fat in Stard13^tm1Ioln/Stard13^tm1Ioln mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152475
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Exon 5 was replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR analysis on heart, liver, and skeletal muscle extracts. (J:152475)

Generation of the Stard13^tm1Ioln allele

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stard13 Mutation: 54 strains or lines available

References

• Original: J:152475 Yau TO, et al., Deleted in liver cancer 2 (DLC2) was dispensable for development and its deficiency did not aggravate hepatocarcinogenesis. PLoS One. 2009;4(8):e6566
• All: 3 reference(s)