Slc34a3^tm1Kimi
Targeted Allele Detail

Summary

• Symbol: Slc34a3^tm1Kimi
• Name: solute carrier family 34 (sodium phosphate), member 3; targeted mutation 1, Ken-ichi Miyamoto
• MGI ID: MGI:4359215
• Synonyms: Npt2c^-
• Gene: Slc34a3 Location: Chr2:25118909-25124282 bp, - strand Genetic Position: Chr2, 17.09 cM
• Alliance: Slc34a3^tm1Kimi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152521
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3(2?) through 5 were replaced with a neomycin resistance cassette. RT-PCR and Western blot analysis confirm the absence of both transcript and protein product. (J:152521)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc34a3 Mutation: 24 strains or lines available

References

• Original: J:152521 Segawa H, et al., Type IIc sodium-dependent phosphate transporter regulates calcium metabolism. J Am Soc Nephrol. 2009 Jan;20(1):104-13
• All: 7 reference(s)