Dync2h1^ttn
Chemically induced Allele Detail

Summary

• Symbol: Dync2h1^ttn
• Name: dynein cytoplasmic 2 heavy chain 1; tian-tian
• MGI ID: MGI:4359237
• Gene: Dync2h1 Location: Chr9:6928550-7177619 bp, - strand Genetic Position: Chr9, Syntenic
• Alliance: Dync2h1^ttn page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Chemically induced (ENU)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induces an A to C substitution in the splice donor site upstream of exon 51. The predicted peptide lacks 38 amino acids from the AAA ATPase domain 4 and is likely to have a strong disruption in gene activity. (J:138139)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dync2h1 Mutation: 215 strains or lines available

References

• Original: J:138139 Ocbina PJ, et al., Intraflagellar transport, cilia, and mammalian Hedgehog signaling: analysis in mouse embryonic fibroblasts. Dev Dyn. 2008 Aug;237(8):2030-8
• All: 3 reference(s)