Mir143^tm1.1Eno
Targeted Allele Detail

Summary

• Symbol: Mir143^tm1.1Eno
• Name: microRNA 143; targeted mutation 1.1, Eric N Olson
• MGI ID: MGI:4359259
• Synonyms: miR-143^-
• Gene: Mir143 Location: Chr18:61782267-61782329 bp, - strand Genetic Position: Chr18, 34.64 cM
• Alliance: Mir143^tm1.1Eno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152458
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The microRNA region was replaced with a floxed and frt-flanked neo cassette. Germline, cre mediated recombination removed the neo cassette. (J:152458)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir143 Mutation: 3 strains or lines available

References

• Original: J:152459 Huby AC, et al., Restoration of podocyte structure and improvement of chronic renal disease in transgenic mice overexpressing renin. PLoS One. 2009;4(8):e6721
• All: 4 reference(s)