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Mir145atm1Eno
Targeted Allele Detail
Summary
Symbol: Mir145atm1Eno
Name: microRNA 145a; targeted mutation 1, Eric N Olson
MGI ID: MGI:4359260
Synonyms: miR-145neo
Gene: Mir145a  Location: Chr18:61780896-61780965 bp, - strand  Genetic Position: Chr18, 34.64 cM
Alliance: Mir145atm1Eno page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:152458
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129S/SvEv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The mircoRNA region was replaced with a floxed and frt-flanked neo cassette. (J:152458)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 7 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Mir145a Mutation:  1 strain or line available
References
Original:  J:152458 Xin M, et al., MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury. Genes Dev. 2009 Sep 15;23(18):2166-78
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory