Pou3f2^tm1Mejr
Targeted Allele Detail

Summary

• Symbol: Pou3f2^tm1Mejr
• Name: POU domain, class 3, transcription factor 2; targeted mutation 1, Dies Meijer
• MGI ID: MGI:4359591
• Synonyms: Brn-2^flox
• Gene: Pou3f2 Location: Chr4:22482780-22488366 bp, - strand Genetic Position: Chr4, 9.73 cM
• Alliance: Pou3f2^tm1Mejr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:83739
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Homologous recombination was used to insert a loxP site 5' to the Pou3f2 and a frt-flanked neomycin gene driven by a thymidine kinase promoter and second loxP site followed by an EGFP gene, inserted into the 3' UTR. (J:83739)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pou3f2 Mutation: 19 strains or lines available

References

• Original: J:83739 Jaegle M, et al., The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes Dev. 2003 Jun 1;17(11):1380-91
• All: 3 reference(s)