Grk4^tm1Rjl
Targeted Allele Detail

Summary

• Symbol: Grk4^tm1Rjl
• Name: G protein-coupled receptor kinase 4; targeted mutation 1, Robert J Lefkowitz
• MGI ID: MGI:4359726
• Synonyms: GRK4 KO
• Gene: Grk4 Location: Chr5:34817723-34912649 bp, + strand Genetic Position: Chr5, 17.91 cM
• Alliance: Grk4^tm1Rjl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152745
• Parent Cell Line: AK7 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A NsiI fragment containing exon 7 was replaced with a neomycin resistance cassette. (J:152745)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Grk4 Mutation: 30 strains or lines available

References

• Original: J:152745 Lefkowitz RJ, Generation of a Grk4 knockout allele. MGI Direct Data Submission. 2009
• All: 2 reference(s)