Dlg4^tm3.1Grnt
Targeted Allele Detail

Summary

• Symbol: Dlg4^tm3.1Grnt
• Name: discs large MAGUK scaffold protein 4; targeted mutation 3.1, Seth G N Grant
• MGI ID: MGI:4359766
• Synonyms: PSD-95^TAP
• Gene: Dlg4 Location: Chr11:69908029-69938107 bp, + strand Genetic Position: Chr11, 42.96 cM, cytoband B4
• Alliance: Dlg4^tm3.1Grnt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152628
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted
• Mutation: Insertion
• Mutation details: The tandem affinity purification (TAP) tag was inserted upstream of the stop codon in exon 19, which was followed by a floxed neo cassette. The neo cassette was removed by germ line, cre mediated recombination. (J:152628)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Dlg4 Mutation: 46 strains or lines available

References

• Original: J:152628 Fernandez E, et al., Targeted tandem affinity purification of PSD-95 recovers core postsynaptic complexes and schizophrenia susceptibility proteins. Mol Syst Biol. 2009;5:269
• All: 4 reference(s)