Camk2b^tm1Yelg
Targeted Allele Detail

Summary

• Symbol: Camk2b^tm1Yelg
• Name: calcium/calmodulin-dependent protein kinase II, beta; targeted mutation 1, Ype Elgersma
• MGI ID: MGI:4359775
• Synonyms: Camk2b^-
• Gene: Camk2b Location: Chr11:5919644-6016362 bp, - strand Genetic Position: Chr11, 3.89 cM
• Alliance: Camk2b^tm1Yelg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152575
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Most of exon 11 and part of intron 11 were replaced with a floxed neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:152575)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Camk2b Mutation: 92 strains or lines available

References

• Original: J:152575 van Woerden GM, et al., betaCaMKII controls the direction of plasticity at parallel fiber-Purkinje cell synapses. Nat Neurosci. 2009 Jul;12(7):823-5
• All: 4 reference(s)