Tg(tetO-Mir208a)#Dzw
Transgene Detail

Summary

• Symbol: Tg(tetO-Mir208a)#Dzw
• Name: transgene insertion #, Da-Zhi Wnag
• MGI ID: MGI:4359827
• Synonyms: TRE-miR-208a
• Transgene: Tg(tetO-Mir208a)#Dzw Location: unknown
• Alliance: Tg(tetO-Mir208a)#Dzw page

Enlarged heart in Tg(tetO-Mir208a)#Dzw/0 Tg(Myh6-tTA)6Smbf/0 mice

Show the 5 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: C57BL/6 x C3H

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Mutation details: Expression of a mouse genomic fragment that includes the coding sequence for the Mir208a precursor was placed under the control of a tetracycline responsive element. Separate lines were generated from 2 founders, this record represents pooled data from both lines. (J:152696)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:152696 Callis TE, et al., MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009 Sep;119(9):2772-86
• All: 2 reference(s)