Klf15^hlb444
Chemically induced Allele Detail

Summary

• Symbol: Klf15^hlb444
• Name: Kruppel-like transcription factor 15; heart, lung and blood, 444
• MGI ID: MGI:4359847
• Synonyms: H340Y
• Gene: Klf15 Location: Chr6:90439558-90452220 bp, + strand
• Alliance: Klf15^hlb444 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: This phenotypic mutant was identified in an ENU mutagenesis screen. The causative mutation is a C to T transition mutation at nucleotide position 1197 in the coding region of Krppel-like Factor 15 (Klf15), resulting in a missense mutation at amino acid 340 in the encoded protein. (J:280739)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klf15 Mutation: 19 strains or lines available

References

• Original: J:77944 JAX National Heart, Lung and Blood Program for Genomic Applications (PGA), Heritable mouse mutants from the JAX NHLBI ENU Mutagenesis Program. MGI Direct Data Submission. 2002
• All: 2 reference(s)