Srrt^tm1.1Thsn
Targeted Allele Detail

Summary

• Symbol: Srrt^tm1.1Thsn
• Name: serrate RNA effector molecule homolog (Arabidopsis); targeted mutation 1.1, Craig B Thompson
• MGI ID: MGI:4360110
• Synonyms: Ars2^flox
• Gene: Srrt Location: Chr5:137293973-137305928 bp, - strand Genetic Position: Chr5, 76.33 cM
• Alliance: Srrt^tm1.1Thsn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152729
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 20. Germ line, flp mediated recombination removed the neo cassettes leaving exons 3 through 20 floxed. (J:152729)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Srrt Mutation: 55 strains or lines available

References

• Original: J:152729 Gruber JJ, et al., Ars2 links the nuclear cap-binding complex to RNA interference and cell proliferation. Cell. 2009 Jul 23;138(2):328-39
• All: 3 reference(s)