Tg(Lck-Fyn*Y528F)5525Cjg
Transgene Detail
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| Symbol: |
Tg(Lck-Fyn*Y528F)5525Cjg |
| Name: |
transgene insertion 5525, Cynthia J Guidos |
| MGI ID: |
MGI:4360310 |
| Synonyms: |
TFF |
| Transgene: |
Tg(Lck-Fyn*Y528F)5525Cjg Location: unknown
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| Alliance: |
Tg(Lck-Fyn*Y528F)5525Cjg page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Lck-Fyn*Y528F)5525Cjg expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Fyn (MGI:95602) |
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Mutation details: The promoter drives T cell-specific expression of a mouse cDNA with nucleotide substitutions that result in the amino acid substitution of phenylalanine for tyrosine at position 528 (Y528F). Line 5525 was generated.
(J:37062)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:37062 Groves T, et al., Fyn can partially substitute for Lck in T lymphocyte development. Immunity. 1996 Nov;5(5):417-28 |
| All: |
1 reference(s) |
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Analysis Tools
