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Tg(Drd1-tdTomato)5Calak
Transgene Detail
Summary
Symbol: Tg(Drd1-tdTomato)5Calak
Name: transgene insertion 5, Nicole Calakos
MGI ID: MGI:4360387
Synonyms: Drd1a-tdTomato, Tg(Drd1a-tdTomato)5Calak
Transgene: Tg(Drd1-tdTomato)5Calak  Location: unknown  
Alliance: Tg(Drd1-tdTomato)5Calak page
Transgene
origin
Strain of Origin:  (C57BL/6 x SJL)F1
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsThe cDNA for a modified DsRed fluorescent protein (designated as tdTomato) along with a synthetic bovine growth hormone polyadenylation signal was inserted into the Drd1a BAC clone RP23-47M2 by homologous recombination in E coli. The tdTomato cDNA replaced the ATG codon as well as an additional 180 bp of coding sequence. Six independent founder lines were established but only line 5 has been reported. (J:123053, J:132997)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:132997 Shuen JA, et al., Drd1a-tdTomato BAC transgenic mice for simultaneous visualization of medium spiny neurons in the direct and indirect pathways of the basal ganglia. J Neurosci. 2008 Mar 12;28(11):2681-5
All:  65 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory